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Publications & Presentations

Paratek is committed to enhancing public health through responsible sharing of clinical trial data.

This page contains links to publications and access to congress presentations  related to our products and may contain information regarding approved and non-approved uses, formulations, or treatment regimens. Information provided is not intended to promote any product or indication. Results reported in any single study may not reflect the overall results obtained across the product development.

Please see the Full Prescribing Information available here.

Download a complete bibliography with links to publications and presentations here.

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Manuscripts
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Posters

Manuscripts

Explore Paratek's Manuscripts below.

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Pharmacokinetics - Pharmacodynamics
Pharmacokinetics, Distribution, Metabolism, and Excretion of Omadacycline Following a Single Intravenous or Oral Dose of 14C-omadacycline in Rats
Resource Type
Manuscript
Areas of Interest
Omadacycline
Author Name
Lin
Citation #
61: e01784-16
Date
December 2016
Review
Discovery, Pharmacology, and Clinical Profile of Omadacycline, A Novel Aminomethylcycline Antibiotic
Resource Type
Manuscript
Areas of Interest
Omadacycline
Author Name
Tanaka
Citation #
24(2016): 6409-6419
Date
December 2016
Microbiology
In Vitro Activities of Omadacycline (PTK 0796) and Other Antimicrobial Agents Against Human Mycoplasmas and Ureaplasmas
Resource Type
Manuscript
Areas of Interest
In Vitro Activity
Author Name
Waites
Citation #
60(12): 7502-7504
Date
November 2016
Pharmacokinetics - Pharmacodynamics
A Randomized, Open-label Study of the Pharmacokinetics and Safety of Oral and Intravenous Administration of Omadacycline to Healthy Subjects
Resource Type
Manuscript
Areas of Interest
Omadacycline
Author Name
Sun
Citation #
60(12): 7431-7435
Date
November 2016
Review
Omadacycline: Development of a Novel Aminomethylcycline Antibiotic for Treating Drug-Resistant Bacterial Infections
Resource Type
Manuscript
Areas of Interest
Omadacycline
Author Name
Villano
Citation #
11(11): 1421-1434
Date
October 2016
Microbiology
The Novel Aminomethylcycline Omadacycline Has High Specificity for the Primary Tetracycline-Binding Site on the Bacterial Ribosome
Resource Type
Manuscript
Areas of Interest
Omadacycline
Author Name
Heidrich
Citation #
5(4): 32
Date
September 2016
Non-Clinical
In Vitro and In Vivo Assessment of Cardiovascular Effects with Omadacycline
Resource Type
Manuscript
Areas of Interest
Omadacycline
Author Name
Tanaka
Citation #
60(9): 5247-5253
Date
August 2016
Pharmacokinetics - Pharmacodynamics
Structure-Activity Relationship of the Aminomethylcyclines and the Discovery of Omadacycline
Resource Type
Manuscript
Areas of Interest
Omadacycline
Author Name
Honeyman
Citation #
59(11): 7044-7053
Date
November 2015
Microbiology
Mechanism of Action of the Novel Aminomethylcycline Antibiotic Omadacycline
Resource Type
Manuscript
Areas of Interest
Omadacycline
Author Name
Draper
Citation #
58(3): 1279–1283
Date
March 2014
In Vitro and In Vivo Antibacterial Activities of Omadacycline, a Novel Aminomethylcycline
Resource Type
Manuscript
Areas of Interest
In Vitro Activity
Author Name
Macone
Citation #
58(2): 1127-1135
Date
February 2014
Clinical
A Randomized, Evaluator-Blind, Phase 2 Study Comparing the Safety and Efficacy of Omadacycline to Those of Linezolid for Treatment of Complicated Skin and Skin Structure Infections
Resource Type
Manuscript
Areas of Interest
Acute Bacterial Skin and Skin Structure Infections (ABSSSI)
Author Name
Noel
Citation #
56(11): 5650-5654
Date
November 2012
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Posters

Explore Paratek's Publications below.

2025
ESCMID Global
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ESCMID Global 2025
2024
IDWeek 2024
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IDWeek 2024
MHSRS
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MHSRS 2024
ASM Microbe
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ASM Microbe 2024
ESCMID Global (formally ECCMID)
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ESCMID Global (formally ECCMID)
Texas Medical Center AMR & Stewardship
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Texas Medical Center AMR & Stewardship
2023
IDWeek
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IDWeek 2023
ECCMID
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ECCMID 2023
2022
IDWeek
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IDWeek 2022
MHSRS
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MHSRS 2022
ASM-Microbe
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ASM-Microbe 2022
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2020
IDWEEK
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IDWEEK 2020
2019
ASM-ESCMID
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ASM-ESCMID 2019
IDWEEK
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IDWEEK 2019
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Activity of omadacycline against multidrug-resistant and molecularly characterized Acinetobacter baumannii-calcoaceticus complex clinical isolates from United States hospitals (2020–2023)
Omadacycline demonstrated efficacy as both therapeutic treatment and post-exposure prophylaxis against inhalation anthrax and pneumonic plague in cynomolgus macaques
Clinical and microbiological outcomes of omadacycline for pulmonary Mycobacterium abscessus complex
Evaluation of Fecal Pharmacokinetics and Metagenomic Changes Following the Administration of Intravenous Omadacycline to Healthy Subjects
Current Prescribing Practices and Guideline Concordance for the Treatment of Community-Acquired Bacterial Pneumonia (CABP) among Outpatient and Urgent Care Visits
In vitro activity of omadacycline and comparator agents against a collection of Neisseria gonorrhoeae urine isolates collected from the United States during 2018-2020
Safety of Omadacycline Versus Standard-of-Care Oral Antibiotic Treatment for Bone and Joint Infections: Interim Results From an Open-Label, Non-Inferiority, Randomized Controlled Trial
Omadacycline is Active Against Multidrug Resistant Bacillus Anthracis Strains Resistant to Tetracyclines
In Vitro Interaction of Omadacycline in Combination with Melatonin against Carbapenemase producing Klebsiella pneumoniae
Evaluation of Omadacycline Treatment for Osteomyelitis
Omadacycline alone and in combination as a treatment option for Mycobacterium avium infections
Minimum inhibitory concentrations (MICs) of tigecycline correlate strongly with those of omadacycline
Real-World Outpatient Use of Omadacycline for Bone and Joint Infections
Early Experience With Omadacycline For The Treatment Of Diabetic Foot Infections
Activity of Omadacycline and Comparators Against 876 Bacterial Clinical Isolates from Patients with Bone and Joint Infections in the United States and Europe (2015–2022)
Omadacycline for the Treatment of Non-Pulmonary Mycobacterial Infections: a Single-Center Retrospective Review
Omadacycline is Efficacious in a Treatment Model of Inhalational Anthrax in New Zealand White Rabbits
In vitro activity of omadacycline and comparator agents against 485 infrequently encountered bacterial pathogens from the SENTRY surveillance programmme
Real-World Use of Omadacycline in Physician Office Infusion Centers (POICs)
A Multi-Center Evaluation of Omadacycline for Multi-Drug Resistant Infections
Preclinical evaluation of omadacycline for potential as a drug to treat Acinetobacter baumannii and Klebsiella pneumoniae infections in combat wounds
In Vitro Activity of Omadacycline against Chlamydia trachomatis Serovars
Phase 2, double-blind, randomized, placebo-controlled, multicenter study to evaluate the efficacy and safety of omadacycline in adults with Mycobacterium abscessus complex (MABc) pulmonary disease
Omadacycline in Female Adults with Acute Pyelonephritis: Results from a Randomized, Double-Blinded, Adaptive Phase 2 Study
Omadacycline in Female Adults with Cystitis: Results from a Randomized, Double-Blinded, Adaptive Phase 2 Study
Pharmacokinetic-Pharmacodynamic (PK-PD) Analyses for Alanine Aminotransferase (ALT) Using Phase 3 Data from Omadacycline (OMC)-Treated Patients
Pharmacokinetic‐Pharmacodynamic (PK‐PD) Analyses for Cardiac Endpoints Using Clinical Study Data from Omadacycline (OMC)‐Treated Patients
Investigating the Interaction between Omadacycline and Other Antibacterial Agents against Gram-Positive and GramNegative Bacteria
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