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Publications & Presentations

Paratek is committed to enhancing public health through responsible sharing of clinical trial data.

This page contains links to publications and access to congress presentations  related to our products and may contain information regarding approved and non-approved uses, formulations, or treatment regimens. Information provided is not intended to promote any product or indication. Results reported in any single study may not reflect the overall results obtained across the product development.

Please see the Full Prescribing Information available here.

Download a complete bibliography with links to publications and presentations here.

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Manuscripts
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Manuscripts

Explore Paratek's Manuscripts below.

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Clinical
Efficacy and safety of optional parenteral antimicrobial therapy for complicated skin and soft tissue infections: A systematic review and Bayesian network meta-analysis
Resource Type
Manuscript
Areas of Interest
Acute Bacterial Skin and Skin Structure Infections (ABSSSI)
Author Name
Li
Citation #
101(34):e30120
Date
August 2022
Real World Evidence
Nebulized bacteriophage in a patient with refractory Mycobacterium abscessus lung disease
Resource Type
Manuscript
Areas of Interest
Nontuberculous Mycobacteria
Author Name
Dedrick
Citation #
9(7): ofac194.
Date
July 2022
Real World Evidence
Omadacycline in first-line combination therapy for pulmonary Mycobacterium abscessus infection: A case series
Resource Type
Manuscript
Areas of Interest
Nontuberculous Mycobacteria
Author Name
Duah
Citation #
S1201-9712(22)00395-2.
Date
July 2022
Real World Evidence
Septic arthritis due to Nocardia brasiliensis and a review of nocardiosis as a cause of arthritis
Resource Type
Manuscript
Areas of Interest
Other
Author Name
Chandramohan
Citation #
29:e01590
Date
July 2022
Non-Clinical
Activity of Omadacycline Alone and in Combination against Carbapenem-Nonsusceptible Acinetobacter baumannii with Varying Minocycline Susceptibility
Resource Type
Manuscript
Areas of Interest
In Vitro Activity
Author Name
Abbey
Citation #
Online ahead of print
Date
June 2022
Microbiology
Effect of Omadacycline Alone and in Combination with Meropenem Against Clinical Acinetobacter baumannii Isolates
Resource Type
Manuscript
Areas of Interest
In Vitro Activity
Author Name
O’Donnell
Citation #
29:147-149
Date
June 2022
Real World Evidence
Difficulty in diagnosis and management of musculoskeletal nontuberculous mycobacterial infections
Resource Type
Manuscript
Areas of Interest
Nontuberculous Mycobacteria
Author Name
Vietor
Citation #
29:e01527
Date
June 2022
Microbiology
Comparison of antibacterial activities and resistance mechanisms of omadacycline and tigecycline against Enterococcus faecium
Resource Type
Manuscript
Areas of Interest
In Vitro Activity
Author Name
Liu
Citation #
75(8):463-471
Date
June 2022
Review
Current Challenges in the Management of Skin and Soft Tissue Infection and Community-Acquired Pneumonia
Resource Type
Manuscript
Areas of Interest
ABSSSI & CABP
Author Name
Lauterio
Citation #
71 (5 Suppl):S2-9
Date
June 2022
Review
Omadacycline in Skin Infections and Pneumonia: A Review of the Evidence
Resource Type
Manuscript
Areas of Interest
ABSSSI & CABP
Author Name
Vacalis
Citation #
71 (5 Suppl):S10-27
Date
June 2022
Clinical
Prevalence and Predictors of Pseudomonas aeruginosa among Hospitalized Patients with Diabetic Foot Infections
Resource Type
Manuscript
Areas of Interest
Diabetic Foot Infections
Author Name
Veve
Citation #
Online
Date
June 2022
Real World Evidence
A Rare Insidious Case of Skin and Soft Tissue Infection Due to Mycobacterium abscessus: A Case Report
Resource Type
Manuscript
Areas of Interest
Nontuberculous Mycobacteria
Author Name
Cardenas
Citation #
14(6):e25725
Date
June 2022
Microbiology
Activity of Omadacycline Alone and in Combination against Carbapenem-Nonsusceptible Acinetobacter baumannii with Varying Minocycline Susceptibility
Resource Type
Manuscript
Areas of Interest
In Vitro Activity
Author Name
Abbey
Citation #
10(3):e0054222
Date
June 2022
Real World Evidence
Real-World, Multicenter Case Series of Patients Treated with Oral Omadacycline for Resistant Gram-Negative Pathogens
Resource Type
Manuscript
Areas of Interest
Multiple
Author Name
Morrisette
Citation #
Online ahead of print
Date
May 2022
Microbiology
In vitro Antibacterial Activity of Cefiderocol against Recent Multidrug-Resistant Carbapenem-nonsusceptible Enterobacterales Isolates
Resource Type
Manuscript
Areas of Interest
In Vitro Activity
Author Name
Zhang
Citation #
103(1):115651
Date
May 2022
Real World Evidence
Host and Pathogen Response to Bacteriophage Engineered against Mycobacterium abscessus Lung Infection
Resource Type
Manuscript
Areas of Interest
Nontuberculous Mycobacteria
Author Name
Nick
Citation #
185(11):1860-1874
Date
May 2022
Real World Evidence
Bacteriophage treatment of disseminated cutaneous Mycobacterium chelonae infection
Resource Type
Manuscript
Areas of Interest
Nontuberculous Mycobacteria
Author Name
Little
Citation #
13, 2313:1-13
Date
May 2022
Real World Evidence
Real-World, Multicenter Case Series of Patients Treated with Oral Omadacycline for Resistant Gram-Negative Pathogens
Resource Type
Manuscript
Areas of Interest
Multiple
Author Name
Morrisette
Citation #
11(4):1715:1723
Date
May 2022
Pharmacokinetics - Pharmacodynamics
Omadacycline Oral Dosing and Pharmacokinetics in Community-Acquired Bacterial Pneumonia and Acute Bacterial Skin and Skin Structure Infection
Resource Type
Manuscript
Areas of Interest
ABSSSI & CABP
Author Name
Leviton
Citation #
42:193-197
Date
April 2022
Pharmacokinetics - Pharmacodynamics
Pharmacokinetics, Safety, and Pharmacokinetics/Pharmacodynamics Analysis of Omadacycline in Chinese Healthy Subjects
Resource Type
Manuscript
Areas of Interest
ABSSSI & CABP
Author Name
Yang
Citation #
21;13:869237.
Date
April 2022
Pharmacokinetics - Pharmacodynamics
Omadacycline Pharmacokinetics and Soft-Tissue Penetration in Diabetic Patients with Wound Infections and Healthy Volunteers using In Vivo Microdialysis
Resource Type
Manuscript
Areas of Interest
Acute Bacterial Skin and Skin Structure Infections (ABSSSI)
Author Name
Gill
Citation #
77(5):1372-1378
Date
April 2022
Microbiology
Omadacycline Efficacy against Streptococcus Agalactiae Isolated in China: Correlation between Resistance and Virulence Gene and Biofilm Formation
Resource Type
Manuscript
Areas of Interest
In Vitro Activity
Author Name
Li
Citation #
7636983
Date
April 2022
Non-Clinical
Omadacycline is Efficacious in the Hollow Fiber System Model of Pulmonary Mycobacterium-avium complex and is Potent at Clinically Attainable Doses
Resource Type
Manuscript
Areas of Interest
Nontuberculous Mycobacteria
Author Name
Chapagain
Citation #
77(6):1694-1705
Date
March 2022
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Posters

Explore Paratek's Publications below.

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2023
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2022
CO Mycobacterium Conference
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Safety of Omadacycline Versus Standard-of-Care Oral Antibiotic Treatment for Bone and Joint Infections: Interim Results From an Open-Label, Non-Inferiority, Randomized Controlled Trial
In vitro activity of omadacycline and comparator agents against a collection of Neisseria gonorrhoeae urine isolates collected from the United States during 2018-2020
Current Prescribing Practices and Guideline Concordance for the Treatment of Community-Acquired Bacterial Pneumonia (CABP) among Outpatient and Urgent Care Visits
Surveillance of omadacycline in vitro activity against 35,000 bacterial clinical isolates from the United States (2019–2023)
Evaluation of Fecal Pharmacokinetics and Metagenomic Changes Following the Administration of Intravenous Omadacycline to Healthy Subjects
Clinical and microbiological outcomes of omadacycline for pulmonary Mycobacterium abscessus complex
Pharmacokinetics of omadacycline in adults with cystic fibrosis
Omadacycline is Active Against Multidrug Resistant Bacillus Anthracis Strains Resistant to Tetracyclines
Evaluation of Omadacycline Treatment for Osteomyelitis
In Vitro Interaction of Omadacycline in Combination with Melatonin against Carbapenemase producing Klebsiella pneumoniae
Omadacycline as Salvage Therapy for Pulmonary Mycobacterium Abscessus Complex
Minimum inhibitory concentrations (MICs) of tigecycline correlate strongly with those of omadacycline
Omadacycline alone and in combination as a treatment option for Mycobacterium avium infections
​​Immunomodulatory activity of omadacycline in vitro and in a murine model of acute lung injury (ALI)
Real-World Outpatient Use of Omadacycline for Bone and Joint Infections
Activity of Omadacycline and Comparators Against 876 Bacterial Clinical Isolates from Patients with Bone and Joint Infections in the United States and Europe (2015–2022)
Early Experience With Omadacycline For The Treatment Of Diabetic Foot Infections
A Functional OMICS Evaluation of Omadacycline to Understand Anti-Clostridioides difficile Protective Effects
Omadacycline for the Treatment of Non-Pulmonary Mycobacterial Infections: a Single-Center Retrospective Review
Omadacycline is Efficacious in a Treatment Model of Inhalational Anthrax in New Zealand White Rabbits
In vitro activity of omadacycline and comparator agents against 485 infrequently encountered bacterial pathogens from the SENTRY surveillance programmme
Gut microbiome diversity and bacterial taxonomic group changes in healthy volunteers receiving oral omadacycline or vancomycin
Quantifying antimycobacterial treatment-related harms among patients with non-tuberculosis Mycobacteria infections: an opportunity for novel agents?
Real-World Use of Omadacycline in Physician Office Infusion Centers (POICs)
In Vitro Activity of Omadacycline against 14,000 Bacterial Isolates from the United States by Infection Type (2020–2021)
A Multi-Center Evaluation of Omadacycline for Multi-Drug Resistant Infections
Bile Acid Concentrations in Healthy Volunteers Receiving Oral Omadacycline or Vancomycin
Preclinical evaluation of omadacycline for potential as a drug to treat Acinetobacter baumannii and Klebsiella pneumoniae infections in combat wounds
In Vitro Activity of Omadacycline against Chlamydia trachomatis Serovars
Phase 2, double-blind, randomized, placebo-controlled, multicenter study to evaluate the efficacy and safety of omadacycline in adults with Mycobacterium abscessus complex (MABc) pulmonary disease
Clinical Response to Intravenous versus Oral Treatment in Patients with Acute Bacterial Skin and Skin Structure Infections
Omadacycline is not a Substrate for Clinically Relevant Beta-Lactamase Enzymes
Omadacycline in Female Adults with Cystitis: Results from a Randomized, Double-Blinded, Adaptive Phase 2 Study
Omadacycline in Female Adults with Acute Pyelonephritis: Results from a Randomized, Double-Blinded, Adaptive Phase 2 Study
Pharmacokinetic-Pharmacodynamic (PK-PD) Analyses for Alanine Aminotransferase (ALT) Using Phase 3 Data from Omadacycline (OMC)-Treated Patients
Pharmacokinetic‐Pharmacodynamic (PK‐PD) Analyses for Cardiac Endpoints Using Clinical Study Data from Omadacycline (OMC)‐Treated Patients
Investigating the Interaction between Omadacycline and Other Antibacterial Agents against Gram-Positive and GramNegative Bacteria
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