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Publications & Presentations

Paratek is committed to enhancing public health through responsible sharing of clinical trial data.

This page contains links to publications and access to congress presentations  related to our products and may contain information regarding approved and non-approved uses, formulations, or treatment regimens. Information provided is not intended to promote any product or indication. Results reported in any single study may not reflect the overall results obtained across the product development.

Please see the Full Prescribing Information available here.

Download a complete bibliography with links to publications and presentations here.

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Manuscripts

Explore Paratek's Manuscripts below.

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Microbiology
Evaluation of Neisseria gonorrhoeae Isolates Susceptibility to Tetracycline Antibiotics from 9 Provinces in China Since 2020
Resource Type
Manuscript
Areas of Interest
Sexually Transmitted Diseases
Author Name
Zhou
Citation #
15:1383-1389.
Date
March 2022
Clinical
Efficacy and Safety of Omadacycline Versus Linezolid in Acute Bacterial Skin and Skin Structure Infections in Persons Who Inject Drugs
Resource Type
Manuscript
Areas of Interest
Acute Bacterial Skin and Skin Structure Infections (ABSSSI)
Author Name
Moran
Citation #
11(1):517-531
Date
February 2022
Microbiology
In Vitro Activity of KBP-7072 against 536 Acinetobacter baumannii Complex Isolates Collected in China
Resource Type
Manuscript
Areas of Interest
In Vitro Activity
Author Name
Han
Citation #
10(1):e0147121
Date
February 2022
Non-Clinical
Potency of Omadacycline against Mycobacteroides abscessus Clinical Isolates In Vitro and in a Mouse Model of Pulmonary Infection
Resource Type
Manuscript
Areas of Interest
Nontuberculous Mycobacteria
Author Name
Nicklas
Citation #
66(1):e0170421
Date
January 2022
Review
Expert Update on Acute Bacterial Skin and Skin Structure Infection Treatment Options in the Community Setting
Resource Type
Manuscript
Areas of Interest
Acute Bacterial Skin and Skin Structure Infections (ABSSSI)
Author Name
Sakoulas
Citation #
71(1)
Date
January 2022
Microbiology
Activity of the Novel Aminomethylcycline KBP-7072 and Comparators against 1,057 Geographically Diverse Recent Clinical Isolates from the SENTRY Surveillance Program, 2019
Resource Type
Manuscript
Areas of Interest
In Vitro Activity
Author Name
Huband
Citation #
66(1):e0139721
Date
January 2022
Microbiology
Multi-lab Comparison of Omadacycline MIC Test Strip to Broth Microdilution MIC Against Gram-negative, Gram-positive and Fastidious Bacteria
Resource Type
Manuscript
Areas of Interest
Omadacycline
Author Name
Koeth
Citation #
60(1):e0141021
Date
January 2022
Non-Clinical
Boromycin has Rapid-Onset Antibiotic Activity Against Asexual and Sexual Blood Stages of Plasmodium falciparum
Resource Type
Manuscript
Areas of Interest
In Vitro Activity
Author Name
de Carvalho
Citation #
11:802294.
Date
January 2022
Non-Clinical
Activity of Omadacycline in Rat Methicillin-Resistant Staphylococcus aureus Osteomyelitis
Resource Type
Manuscript
Areas of Interest
Bone and Joint Infections
Author Name
Karau
Citation #
66(1):e0170321
Date
January 2022
Microbiology
Sub-inhibitory Concentrations of Omadacycline Inhibit Staphylococcus aureus Haemolytic Activity In Vitro
Resource Type
Manuscript
Areas of Interest
ABSSSI & CABP
Author Name
Serio
Citation #
4(1):dlab190
Date
December 2021
Real World Evidence
Health-Related Quality of Life as Measured by the 36-item Short Form Survey Among Adults with Acute Bacterial Skin and Skin Structure Infections Who Received Either Omadacycline or Linezolid in a Phase 3 Double-Blind, Double-Dummy Clinical Trial
Resource Type
Manuscript
Areas of Interest
Acute Bacterial Skin and Skin Structure Infections (ABSSSI)
Author Name
Chitra
Citation #
8(10):ofab459
Date
December 2021
Non-Clinical
Omadacycline Potentiates Clarithromycin Activity Against Mycobacterium abscessus
Resource Type
Manuscript
Areas of Interest
Nontuberculous Mycobacteria
Author Name
Hanh
Citation #
13191:27:00
Date
December 2021
Microbiology
Surveillance of Omadacycline Activity Tested Against Clinical Isolates from the USA: Report from the SENTRY Antimicrobial Surveillance Program, 2019
Resource Type
Manuscript
Areas of Interest
ABSSSI & CABP
Author Name
Pfaller
Citation #
337-351
Date
December 2021
Microbiology
Novel Tet(L) Efflux Pump Variants Conferring Resistance to Tigecycline and Eravacycline in Staphylococcus Spp.
Resource Type
Manuscript
Areas of Interest
In Vitro Activity
Author Name
Wang
Citation #
9(3):e0131021
Date
December 2021
Microbiology
In Vitro Activity of Omadacycline and Five Comparators against Contemporary Ribotypes of Clostridioides difficile in Stockholm, Sweden
Resource Type
Manuscript
Areas of Interest
Clostridioides difficile
Author Name
Camporeale
Citation #
9(2):e0144021
Date
October 2021
Pharmacokinetics - Pharmacodynamics
Inadequate Cerebrospinal Fluid Concentrations of Available Salvage Agents Further Impedes the Optimal Treatment of Multidrug-Resistant Enterococcus faecium Meningitis and Bacteremia
Resource Type
Manuscript
Areas of Interest
In Vitro Activity
Author Name
Wenzler
Citation #
13(3):843-854
Date
September 2021
Non-Clinical
Efficacy of Omadacycline Against Multiresistant Enterococcus faecium Strains in a Mouse Peritonitis Model
Resource Type
Manuscript
Areas of Interest
In Vitro Activity
Author Name
Singh
Citation #
65(9):e00709-21
Date
August 2021
Clinical
Safety and Efficacy of Omadacycline by Body Mass Index in Patients with Community-Acquired Bacterial Pneumonia: Subanalysis from a Randomized Controlled Trial
Resource Type
Manuscript
Areas of Interest
Community Acquired Bacterial Pneumonia (CABP)
Author Name
Pai
Citation #
1958:02:00
Date
August 2021
Microbiology
In Vitro Susceptibility of Rickettsia Species to Eravacycline, Omadacycline and Tigecycline
Resource Type
Manuscript
Areas of Interest
In Vitro Activity
Author Name
Quade
Citation #
65(8):e00665-21
Date
July 2021
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Posters

Explore Paratek's Publications below.

2024
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2023
ECCMID
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ASM Microbe
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2022
CO Mycobacterium Conference
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Safety of Omadacycline Versus Standard-of-Care Oral Antibiotic Treatment for Bone and Joint Infections: Interim Results From an Open-Label, Non-Inferiority, Randomized Controlled Trial
In vitro activity of omadacycline and comparator agents against a collection of Neisseria gonorrhoeae urine isolates collected from the United States during 2018-2020
Current Prescribing Practices and Guideline Concordance for the Treatment of Community-Acquired Bacterial Pneumonia (CABP) among Outpatient and Urgent Care Visits
Surveillance of omadacycline in vitro activity against 35,000 bacterial clinical isolates from the United States (2019–2023)
Evaluation of Fecal Pharmacokinetics and Metagenomic Changes Following the Administration of Intravenous Omadacycline to Healthy Subjects
Clinical and microbiological outcomes of omadacycline for pulmonary Mycobacterium abscessus complex
Pharmacokinetics of omadacycline in adults with cystic fibrosis
Omadacycline is Active Against Multidrug Resistant Bacillus Anthracis Strains Resistant to Tetracyclines
Evaluation of Omadacycline Treatment for Osteomyelitis
In Vitro Interaction of Omadacycline in Combination with Melatonin against Carbapenemase producing Klebsiella pneumoniae
Omadacycline as Salvage Therapy for Pulmonary Mycobacterium Abscessus Complex
Minimum inhibitory concentrations (MICs) of tigecycline correlate strongly with those of omadacycline
Omadacycline alone and in combination as a treatment option for Mycobacterium avium infections
​​Immunomodulatory activity of omadacycline in vitro and in a murine model of acute lung injury (ALI)
Real-World Outpatient Use of Omadacycline for Bone and Joint Infections
Activity of Omadacycline and Comparators Against 876 Bacterial Clinical Isolates from Patients with Bone and Joint Infections in the United States and Europe (2015–2022)
Early Experience With Omadacycline For The Treatment Of Diabetic Foot Infections
A Functional OMICS Evaluation of Omadacycline to Understand Anti-Clostridioides difficile Protective Effects
Omadacycline for the Treatment of Non-Pulmonary Mycobacterial Infections: a Single-Center Retrospective Review
Omadacycline is Efficacious in a Treatment Model of Inhalational Anthrax in New Zealand White Rabbits
In vitro activity of omadacycline and comparator agents against 485 infrequently encountered bacterial pathogens from the SENTRY surveillance programmme
Gut microbiome diversity and bacterial taxonomic group changes in healthy volunteers receiving oral omadacycline or vancomycin
Quantifying antimycobacterial treatment-related harms among patients with non-tuberculosis Mycobacteria infections: an opportunity for novel agents?
Real-World Use of Omadacycline in Physician Office Infusion Centers (POICs)
In Vitro Activity of Omadacycline against 14,000 Bacterial Isolates from the United States by Infection Type (2020–2021)
A Multi-Center Evaluation of Omadacycline for Multi-Drug Resistant Infections
Bile Acid Concentrations in Healthy Volunteers Receiving Oral Omadacycline or Vancomycin
Preclinical evaluation of omadacycline for potential as a drug to treat Acinetobacter baumannii and Klebsiella pneumoniae infections in combat wounds
In Vitro Activity of Omadacycline against Chlamydia trachomatis Serovars
Phase 2, double-blind, randomized, placebo-controlled, multicenter study to evaluate the efficacy and safety of omadacycline in adults with Mycobacterium abscessus complex (MABc) pulmonary disease
Clinical Response to Intravenous versus Oral Treatment in Patients with Acute Bacterial Skin and Skin Structure Infections
Omadacycline is not a Substrate for Clinically Relevant Beta-Lactamase Enzymes
Omadacycline in Female Adults with Cystitis: Results from a Randomized, Double-Blinded, Adaptive Phase 2 Study
Omadacycline in Female Adults with Acute Pyelonephritis: Results from a Randomized, Double-Blinded, Adaptive Phase 2 Study
Pharmacokinetic-Pharmacodynamic (PK-PD) Analyses for Alanine Aminotransferase (ALT) Using Phase 3 Data from Omadacycline (OMC)-Treated Patients
Pharmacokinetic‐Pharmacodynamic (PK‐PD) Analyses for Cardiac Endpoints Using Clinical Study Data from Omadacycline (OMC)‐Treated Patients
Investigating the Interaction between Omadacycline and Other Antibacterial Agents against Gram-Positive and GramNegative Bacteria
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